Brain Tumor Causes

types of radiation therapy for brain tumors

brain tumor
Written by admin

The brain tumor is the growth of abnormal cells in the brain. There are many types of treatments available for a brain tumor. Its selection depends upon the age of the patient, size of the tumor, type and stage of cancer, the health status of a patient and other environmental factors. The choice of treatment is very important because the chances of recovery lie in its selection. Some patients become confused and select a wrong one for them. If you have gotten any type of cancer, you should go to a specialist for proper medical checkups and then discuss the type of treatment. Following are some important treatment options:

  • Temozolomide
  • Radiotherapy
  • Radiosurgery
  • Neurosurgery
  • Craniotomy


It is the use of ionizing radiations to destroy the tumor. It is more favorable when the tumor is not spreading to other organs. It is also used as a part of surgery to prevent recurrence of the tumor. It is useful with chemotherapy and doctors to use it before, after and during chemotherapy in susceptible cancer.

Mechanism of tumor destruction by radiation

It can control cell division of abnormal cells by damaging their DNA and causing the death of these cells. It is applied in a manner that normal cells remain intact from radiations and effected cells absorb them as maximum as possible. For this purpose, radiationsapplied at such an angle that they intercept with the tumor. When they hit the DNA of abnormal cells, they destroy them and as a result, the cells start to die.

2- Neurosurgery

Neurosurgery is also known as neurological surgery. It is a medical specialty, which concerns with the diagnosis, prevention, rehabilitation of diseases and surgical treatment. It affects all parts of the nervous system like the spinal cord, brain, extracranial cerebrovascular system, and peripheral nerves.

3- Radiosurgery

It is a type of surgery, which use radiations to destroy the tumor cells in a selected part of the body. It uses ionizing radiations for excision instead of a blade for a cut. A Swedish neurosurgeon Lars Leksell first used this methodas a fractional dose of radiations directed toward an area of interest.

Sources of radiations for radiotherapy and radiosurgery

Its selection depends upon many important factors like the size of the tumor, type of lesion and location of the tumor. Gamma knife is a very important source that uses gamma rays for treatment.

4- Craniotomy

It is an operation to remove a bone flap from the skull for accessing to the brain. These are usually difficult operations and just perform on patients who have serious brain injury and lesions. It is useful in the treatment of epilepsy, cerebellar tumor, and Parkinson’s disease by helping in the implantation of deep brain stimulators. It helps in neuroscience for neurological manipulations, extracellular recording and brain imaging like chemical titration and electrical stimulation.

5- Temozolomide

It is a chemotherapeutic drug for the oral disorder.

Mechanism of action

Its action lies in its ability to methylate or alkylate the DNA on O-6 or N-7 residue of guanine. DNA damages due to this methylation and consequently lead to the death of abnormal cells. Some cells have active DNA repairing mechanism. They repair the damage and do not die. They decrease the therapeutic effect of this drug.

About the author


Leave a Comment